The applications of polyphenol hydrogels mainly include wound healing, tumor treatment, treatment of musculoskeletal diseases, treatment of digestive system diseases, treatment of eye diseases, spinal cord injury repair, bioelectronics, sun protection, and skincare. Taking wound healing as an example (Figure 3), an ideal wound healing material should have hemostatic, antibacterial, and anti-inflammatory effects. Polyphenolic compounds can endow polyphenol hydrogels with adhesiveness, self-healing ability, bioaffinity, antibacterial properties, and antioxidant properties, and also make the hydrogels excellent drug delivery carriers, thereby meeting the requirements of wound healing materials.
